Difference between revisions of "Caprine Arthritis Encephalitis Virus"
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*Treat mother's '''colostrum''' (56 deg for 1 hour) | *Treat mother's '''colostrum''' (56 deg for 1 hour) | ||
*Rear on artificial milk | *Rear on artificial milk | ||
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| + | ===Caprine Arthritis-Encephalitis (CAE)=== | ||
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| + | *Caused by [[Retroviridae|retrovirus (lentivirus)]] similar to [[Respiratory Viral Infections - Pathology#Maedi Visna|Maedi Visna]] in sheep described above | ||
| + | *Two forms: | ||
| + | **Non-suppurative leukoencephalomyelitis in young goats and kids | ||
| + | **Chronic, non-suppurative arthritis-synovitis in adult goats | ||
| + | *Also causes [[Lungs Inflammatory - Pathology#Interstitial pneumonia|interstitial pneumonia]] which tends to be obscured by other clinical signs | ||
| + | *Gross pathology: | ||
| + | **Mainly caudal lobes | ||
| + | **Lungs are firm, grey-pink with grey-white focal lesions on cut surface | ||
| + | *Micro pathology: | ||
| + | **Thickened alveolar wall | ||
| + | **Lymphocyte infiltration and type II pneumocyte hyperplasia | ||
| + | *Can be confused with or coexisting with [[Lungs Inflammatory - Pathology#Verminous pneumonia|Parasitic pneumonia]] | ||
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[[Category:Lentiviruses]][[Category:Goat]][[Category:To_Do_-_Viruses]] | [[Category:Lentiviruses]][[Category:Goat]][[Category:To_Do_-_Viruses]] | ||
Revision as of 12:15, 30 June 2010
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This article is still under construction. |
CAEV
Antigenicity
- Serologically related to Visna-Maedi with antigenic and genetic envelope differences
Hosts
- Goats
Pathogenesis
- T cells induce immune complex disease
- Causes encephalitis of kids or insidious polyarthritis of adults
- Also causes pneumonia
Epidemiology
- Transfer via milk and colostrum, particularly batch-mixing
- Present in 10% of UK herds
- Clinical disease is rare
Diagnosis
- Visna-Maedi serology (ELISA) test can be used to remove positive stock
Control
- Separate kids from virus positive mothers at birth
- Treat mother's colostrum (56 deg for 1 hour)
- Rear on artificial milk
Caprine Arthritis-Encephalitis (CAE)
- Caused by retrovirus (lentivirus) similar to Maedi Visna in sheep described above
- Two forms:
- Non-suppurative leukoencephalomyelitis in young goats and kids
- Chronic, non-suppurative arthritis-synovitis in adult goats
- Also causes interstitial pneumonia which tends to be obscured by other clinical signs
- Gross pathology:
- Mainly caudal lobes
- Lungs are firm, grey-pink with grey-white focal lesions on cut surface
- Micro pathology:
- Thickened alveolar wall
- Lymphocyte infiltration and type II pneumocyte hyperplasia
- Can be confused with or coexisting with Parasitic pneumonia