Difference between revisions of "Bordetella bronchiseptica"

Revision as of 14:15, 30 June 2010

B. bronchiseptica causes Atrophic rhinitis of pigs in association with Pasteurella multocida
Colonises nasopharynx
Infection must occur during first few weeks of life
Produces dermonecrotic toxin which damages osteoblasts, preventing bone formation
Leads to turbinate atrophy without distortion of the snout in uncomplicated infections
Atrophic rhinitis results when Pasteurella multocida colonises and produces osteolytic toxin, leading to bone resorption
Malformation of snout in growing pigs as well as poor growth
increases with high stocking density and poor ventilation
Vaccine available

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-===Infectious canine tracheitis/Kennel cough===
+===[[Infectious Canine Tracheitis]]/Kennel cough===
-*''B. bronchiseptica'' acts as a primary pathogen in [[Respiratory Viral Infections - Pathology#Infectious canine tracheitis|Infectious canine tracheitis]]
-*Frequently isolated from dogs with respiratory disease
-*Often found with viruses or mycoplasma
-*Adheres to ciliated epithelial cells in the trachea
-*Colonisation and proliferation in trachea
-*Releases toxins causing epithelial necrosis and prevents ciliary clearance
-*Irritation to tract causes coughing
-*Mortality rates low
-*Peribronchial inflammation and [[Lungs Inflammatory - Pathology#Bronchopneumonia|bronchopneumonia]]
-can result in unvaccinated puppies or immunosuppressed dogs
-*Severe pneumonia following secondary infection e.g. with [[:Category:Streptococcus species|Streptococci]]
-*Fatal [[Lungs Inflammatory - Pathology#Bronchopneumonia|bronchopneumonia]] if occurs secondary to [[Paramyxoviridae#Canine distemper virus|canine distemper virus]]
-*Transmission via respiratory secretions by direct contact or aerosol and on fomites
-*Clinical signs:
-**Develop within 3-4 days; persist for up to 2 weeks
-**Coughing
-**Gagging
-**Mild serous oculonasal discharge
-*Treatments includes antibiotics if coughing persists or bronchopneumonia develops
-*Live intranasal vaccines
-*Also found in respiratory tract of cats; can cause pneumonia in kittens; vaccine available
 ===Atrophic Rhinitis===