Difference between revisions of "Infectious Canine Hepatitis"
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==Description== | ==Description== | ||
| + | *adenovirus - [[Canine Adenovirus 1]] | ||
| + | *acute and generalised infection | ||
| + | *highly infectious | ||
| + | *spread via the urine of infected animals over a long period of time | ||
==Signalment== | ==Signalment== | ||
| − | + | *young dogs | |
==Diagnosis== | ==Diagnosis== | ||
| − | ==Clinical Signs== | + | ===Clinical Signs=== |
| − | + | *recovering animals may show an immune-mediated uveitis with corneal opacity | |
| − | ==Laboratory Tests== | + | ===Laboratory Tests=== |
| − | ==Radiography== | + | ===Radiography=== |
| − | ==Biopsy== | + | ===Biopsy=== |
| − | ==Endoscopy== | + | ===Endoscopy=== |
| − | ==Pathology= | + | ===Pathology=== |
| − | + | ====Gross==== | |
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*the virus has a tropism for endothelium and hepatocytes | *the virus has a tropism for endothelium and hepatocytes | ||
**widespread haemorrhages, especially on serosal surface | **widespread haemorrhages, especially on serosal surface | ||
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*[[Gall Bladder - Anatomy & Physiology|gall bladder]] | *[[Gall Bladder - Anatomy & Physiology|gall bladder]] | ||
**wall usually shows oedema (up to 2cm diameter) | **wall usually shows oedema (up to 2cm diameter) | ||
| − | + | *[[Lymph Nodes - Anatomy & Physiology|lymph nodes]] and [[Tonsils - Anatomy & Physiology|tonsils]] are enlarged and reddened, sometimes haemorrhagic | |
| − | + | ====Microscopically==== | |
*basophilic intranuclear inclusion bodies | *basophilic intranuclear inclusion bodies | ||
**in hepatocytes and macrophages | **in hepatocytes and macrophages | ||
| + | ==Treatment== | ||
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| + | ==Prognosis== | ||
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| + | ==References== | ||
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[[Category:Hepatitis, Viral]][[Category:Dog]][[Category:To_Do_-_Clinical]] | [[Category:Hepatitis, Viral]][[Category:Dog]][[Category:To_Do_-_Clinical]] | ||
[[Category:To_Do_-_Lizzie]] | [[Category:To_Do_-_Lizzie]] | ||
Revision as of 14:38, 5 July 2010
 |
This article is still under construction. |
| Also known as: | Rubarth's Disease Canine adenovirus infection |
Description
- adenovirus - Canine Adenovirus 1
- acute and generalised infection
- highly infectious
- spread via the urine of infected animals over a long period of time
Signalment
- young dogs
Diagnosis
Clinical Signs
- recovering animals may show an immune-mediated uveitis with corneal opacity
Laboratory Tests
Radiography
Biopsy
Endoscopy
Pathology
Gross
- the virus has a tropism for endothelium and hepatocytes
- widespread haemorrhages, especially on serosal surface
- distinctly pale mottled appearance
- from extensive necrosis, characteristically periacinar (centrilobular) in distribution - the reason for the increased susceptibility of this area is not known
- enlarged
- friable
- fibrinous or fibrino-haemorrhagic strands between lobes
- gall bladder
- wall usually shows oedema (up to 2cm diameter)
- lymph nodes and tonsils are enlarged and reddened, sometimes haemorrhagic
Microscopically
- basophilic intranuclear inclusion bodies
- in hepatocytes and macrophages