Difference between revisions of "Innate Immunity Flashcards"

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|q1=True or False: The innate immune system responds quicker to infection than the adaptive immune system
 
|q1=True or False: The innate immune system responds quicker to infection than the adaptive immune system
 
|a1=True
 
|a1=True
|l1=Innate Immune System - WikiBlood#Introduction
+
|l1=Innate Immune System - Introduction
 
|q2=Pathogen-associated molecular patterns (PAMPs) are expressed by which type of cells?
 
|q2=Pathogen-associated molecular patterns (PAMPs) are expressed by which type of cells?
 
|a2=
 
|a2=
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*Mannose sugars  
 
*Mannose sugars  
 
*D-isoform amino acids  
 
*D-isoform amino acids  
|l2=Innate Immune System - WikiBlood#Recognition of Microorganisms
+
|l2=Recognition of Microorganisms
 
|q3=What recognises PAMPs?
 
|q3=What recognises PAMPs?
 
|a3=Pattern recognition receptors (PRRs)
 
|a3=Pattern recognition receptors (PRRs)
|l3=Innate Immune System - WikiBlood#Recognition of Microorganisms
+
|l3=Recognition of Microorganisms
 
|q4=Where in the cell are Toll-Like Receptors (TLRs) located?
 
|q4=Where in the cell are Toll-Like Receptors (TLRs) located?
 
|a4=Cell membrane
 
|a4=Cell membrane
|l4=Innate Immune System - WikiBlood#Recognition of Microorganisms
+
|l4=Recognition of Microorganisms
 
|q5=Where in the cell are NOD2 receptors located?
 
|q5=Where in the cell are NOD2 receptors located?
 
|a5=Cell cytoplasm
 
|a5=Cell cytoplasm
|l5=Innate Immune System - WikiBlood#Recognition of Microorganisms
+
|l5=Recognition of Microorganisms
 
|q6=Which catabolic enzymes digest microbes after phagocytosis?
 
|q6=Which catabolic enzymes digest microbes after phagocytosis?
 
|a6=
 
|a6=
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*Lipases
 
*Lipases
 
*Proteases
 
*Proteases
|l6=Innate Immune System - WikiBlood#Phagocytosis
+
|l6=Phagocytosis
 
|q7=True or False: Lysosomes do not use energy when they kill microbes
 
|q7=True or False: Lysosomes do not use energy when they kill microbes
 
|a7=
 
|a7=
 
*False
 
*False
 
*Lysosomes fuse with phagosomes, killing microbes in an energy-dependent way
 
*Lysosomes fuse with phagosomes, killing microbes in an energy-dependent way
|l7=Innate Immune System - WikiBlood#Phagocytosis
+
|l7=Phagocytosis
 
|q8=Name two physical barriers of the innate immune system
 
|q8=Name two physical barriers of the innate immune system
 
|a8=
 
|a8=
 
*Skin
 
*Skin
 
*Mucous membranes
 
*Mucous membranes
|l8=Innate Immune System - WikiBlood#Pysical Barriers
+
|l8=Innate Immune System Barriers
 
|q9=Name 3 biochemical barriers of the innate immune system
 
|q9=Name 3 biochemical barriers of the innate immune system
 
|a9=
 
|a9=
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*Enzymes
 
*Enzymes
 
*Mucous
 
*Mucous
|l9=Innate Immune System - WikiBlood#Biochemical Barriers
+
|l9=Innate Immune System Barriers
 
|q10=What is the function of commensal organisms?
 
|q10=What is the function of commensal organisms?
 
|a10=
 
|a10=
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*Interferons
 
*Interferons
 
**=Make uninfected cells resistant to infection
 
**=Make uninfected cells resistant to infection
|l12=Innate Immune System - WikiBlood#Humoral Factors
+
|l12=Innate Immune System Humoral Factors
 
|q13=Which granulocytes are components of the innate immune response to infection?
 
|q13=Which granulocytes are components of the innate immune response to infection?
 
|a13=
 
|a13=
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*Eosinophils
 
*Eosinophils
 
*Basophils/mast cells  
 
*Basophils/mast cells  
|l13=Innate Immune System - WikiBlood#Cellular responses
+
|l13=Innate Immune System Cellular Responses
 
|q14=Which other cells are components of the innate immune response to infection?
 
|q14=Which other cells are components of the innate immune response to infection?
 
|a14=Monocytes
 
|a14=Monocytes
 
*Tissue mast cells
 
*Tissue mast cells
 
*Macrophages  
 
*Macrophages  
|l14=Innate Immune System - WikiBlood#Cellular responses
+
|l14=Innate Immune System Cellular Responses
 
</FlashCard>
 
</FlashCard>
 
===Innate Immunity to Viruses===
 
===Innate Immunity to Viruses===
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|q1=What is the main element of a viral attack which the innate immune system can recognise?
 
|q1=What is the main element of a viral attack which the innate immune system can recognise?
 
|a1=Double stranded RNA (dsRNA)
 
|a1=Double stranded RNA (dsRNA)
|l1=Innate Immune System - WikiBlood#Innate Immunity to Viruses
+
|l1=Innate Immunity to Viruses
 
|q2=Where are TLR3's located in the cell and what do they recognise?
 
|q2=Where are TLR3's located in the cell and what do they recognise?
 
|a2=
 
|a2=
 
*Cell surface
 
*Cell surface
 
*Double stranded RNA (dsRNA)
 
*Double stranded RNA (dsRNA)
|l2=Innate Immune System - WikiBlood#Innate Immunity to Viruses
+
|l2=Innate Immunity to Viruses
 
|q3=What are the funtions of Type I Interferon production in response to a viral attack?
 
|q3=What are the funtions of Type I Interferon production in response to a viral attack?
 
|a3=
 
|a3=
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*Inhibits protein synthesis
 
*Inhibits protein synthesis
 
*Increases antigen presentation to antibody
 
*Increases antigen presentation to antibody
|l3=Innate Immune System - WikiBlood#Innate Immunity to Viruses
+
|l3=Innate Immunity to Viruses
 
|q4=Which cells are produced as the final line of response to viral attack and which cells do they target?
 
|q4=Which cells are produced as the final line of response to viral attack and which cells do they target?
 
|a4=
 
|a4=
 
*Natural Killer cells (NK cells)
 
*Natural Killer cells (NK cells)
 
*Targets cells with decreased levels of MHC on their surface
 
*Targets cells with decreased levels of MHC on their surface
|l4=Innate Immune System - WikiBlood#Innate Immunity to Viruses
+
|l4=Innate Immunity to Viruses
 
</FlashCard>
 
</FlashCard>
 
===Innate Immunity to Bacteria===
 
===Innate Immunity to Bacteria===
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*Mediates the release of acute phase proteins from the liver
 
*Mediates the release of acute phase proteins from the liver
 
*Mediates boone marrow mobilisation
 
*Mediates boone marrow mobilisation
|l1=Innate Immune System - WikiBlood#Innate Immunity to Bacteria
+
|l1=Innate Immunity to Bacteria
 
|q2=Which cell is most important in the innate response to bacterial infection?
 
|q2=Which cell is most important in the innate response to bacterial infection?
 
|a2=Neutrophils
 
|a2=Neutrophils
|l2=Innate Immune System - WikiBlood#Innate Immunity to Bacteria
+
|l2=Innate Immunity to Bacteria
 
</FlashCard>
 
</FlashCard>
  

Revision as of 16:24, 13 August 2010

Actions and Tools of the Innate Immune System

Question Answer Article
True or False: The innate immune system responds quicker to infection than the adaptive immune system Link to Article
Pathogen-associated molecular patterns (PAMPs) are expressed by which type of cells? Link to Article
What recognises PAMPs? Link to Article
Where in the cell are Toll-Like Receptors (TLRs) located? Link to Article
Where in the cell are NOD2 receptors located? Link to Article
Which catabolic enzymes digest microbes after phagocytosis? Link to Article
True or False: Lysosomes do not use energy when they kill microbes Link to Article
Name two physical barriers of the innate immune system Link to Article
Name 3 biochemical barriers of the innate immune system Link to Article
What is the function of commensal organisms? Link to Article
Complete the sentence about commensal organisms:

When commensals are disturbed, infection with ??? organisms is ???

Link to Article
Name the three main humoral factors and their principal action Link to Article
Which granulocytes are components of the innate immune response to infection? Link to Article
Which other cells are components of the innate immune response to infection? Link to Article


Innate Immunity to Viruses

Question Answer Article
What is the main element of a viral attack which the innate immune system can recognise? Link to Article
Where are TLR3's located in the cell and what do they recognise? Link to Article
What are the funtions of Type I Interferon production in response to a viral attack? Link to Article
Which cells are produced as the final line of response to viral attack and which cells do they target? Link to Article


Innate Immunity to Bacteria

Question Answer Article
What effects does the release of inflammatory cytokines have on the infected area? Link to Article
Which cell is most important in the innate response to bacterial infection? Link to Article