Changes

**Foreign organisms are internalised

**Foreign organisms are internalised

** Within the dendritic cells, antigen is digested to peptides

** Within the dendritic cells, antigen is digested to peptides

** Some of the peptides formed bind to the cell’s [[Adaptive Immune System - WikiBlood#Structure and Function of MHC Class I|MHC]] molecules

** Some of the peptides formed bind to the cell’s [[MHC]] molecules

*The Langerhans cells leave the epithelium and travel via the afferent lymph. They are now called '''Veiled Cells'''

*The Langerhans cells leave the epithelium and travel via the afferent lymph. They are now called '''Veiled Cells'''

* The CTl killing mechanism is initiated by direct CTL-target cell contact.   

* The CTl killing mechanism is initiated by direct CTL-target cell contact.   

* The cells involved bind by antigen/[[Adaptive Immune System - WikiBlood#Structure and Function of MHC Class I|MHC]] class I-TcR interaction.

* The cells involved bind by antigen/[[MHC]] class I-TcR interaction.

** This results in the CTL's intracellular granules becoming localised to the area of contact.  

** This results in the CTL's intracellular granules becoming localised to the area of contact.  

*** These granules contain most of the molecules responsible for cytotoxicity.  

*** These granules contain most of the molecules responsible for cytotoxicity.  

[[Lymphocytes#Cytotoxic CD8+|Lymphocytes]]

[[Lymphocytes#Cytotoxic CD8+|Lymphocytes]]

[[Adaptive Immune System - WikiBlood#Structure and Function of MHC Class I|Major Histocompatability Complex (MHC) molecule]]

[[MHC|Major Histocompatability Complex (MHC) molecule]]

[[Category:Lymphocytes|G]]

[[Category:Lymphocytes|G]]