Difference between revisions of "Nuclear Transplantation/Cloning - Anatomy & Physiology"
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|linktext =Reproductive System | |linktext =Reproductive System | ||
|maplink = Reproductive System (Content Map) - Anatomy & Physiology | |maplink = Reproductive System (Content Map) - Anatomy & Physiology | ||
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|sublink1=Reproductive System - Anatomy & Physiology#Reproductive Technologies | |sublink1=Reproductive System - Anatomy & Physiology#Reproductive Technologies | ||
|subtext1=REPRODUCTIVE TECHNOLOGIES | |subtext1=REPRODUCTIVE TECHNOLOGIES | ||
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* Cloned individuals have a high percentage of developmental abnormalities. | * Cloned individuals have a high percentage of developmental abnormalities. | ||
** Often associated with [[Joints Inflammatory - Pathology#Arthritis|Arthritis]] and [[Joints Inflammatory - Pathology|Joint problems]]. | ** Often associated with [[Joints Inflammatory - Pathology#Arthritis|Arthritis]] and [[Joints Inflammatory - Pathology|Joint problems]]. | ||
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Revision as of 12:35, 31 August 2010
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- Commonly used in mice to propagate required characteristics.
- Embryonic stem cells are used as a source of totipotent nuclei, which are capable of dividing into a range of new cells.
- These cells are fused with pre-ovulatory oocytes which have had their own haploid nucleus removed using electrofusion.
- Cells are artificially stimulated to the second meiotic division and begin embryonic development.
- The cell source ,capable of replication in culture, can be stored by freezing and is therefore 'immortal' and able to produce many identical individuals.
- Cloned individuals have a high percentage of developmental abnormalities.
- Often associated with Arthritis and Joint problems.