Difference between revisions of "Reproductive Hormones Overview - Anatomy & Physiology"
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Revision as of 17:25, 1 December 2010
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Name of Hormone | Gonadotrophin Releasing Hormone | Leutinizing Hormone | Follicle Stimulating Hormone | Prolactin | Oxytocin | Oestradiol | Progesterone | Testosterone | Inhibin | Activin | Prostaglandin F2α | Human Chorionic Gonadotrophin | Equine Chorionic Gonadotrophin | Placental Lactogen | ||
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Abbreviation | GnRH | LH | FSH | PRL | OT | E2 | P4 | T | PGF2α | PGE2 | hCG | eCG | PL | |||
Biochemical Classification | Neuropeptide (decapeptide) | Glycoprotein | Glycoprotein | Protein | Neuropeptide (Octapeptide) | Steroid | Steroid | Steroid | Glycoprotein | Glycoprotein | Prostaglandin (C20 fatty acid) | Prostaglandin (C20 fatty acid) | Glycoprotein | Glycoprotein | Protein | |
Source | Hypothalamic Surge and Tonic Centres | Anterior Pituitary (Gonadotroph Cells) | Anterior Pituitary (Gonadotroph Cells) | Anterior Pituitary (Lactotroph Cells) | Synthesized in the Hypothalamus, Stored in the Posterior Pituitary, Synthesized by the Corpus Luteum | Granulosa Cells of Follicle, Placenta and Sertoli Cells of Testes | Corpus Luteum and Placenta | Interstitial Leydig Cells of Testes, Theca Interna Cells of the Follicle | Granulosa Cells (female), Sertoli Cells (male) | Granulosa Cells (female), Sertoli Cells (male) | Uterine Endometrium, Vesicular Glands | Ovary, Uterus, Embryonic Membranes | Trophoblast Cells of the Blastocyst (Chorion) | Chorionic Girdle Cells | Placenta | |
Male Target Tissue | Anterior Pituitary (Gonadotroph Cells) | Testes (Leydig Cells) | Testes (Sertoli Cells) | Testes, Brain | Smooth Muscle of Epididymal Tail, Ductus Deferens, Ampulla | Brain, Inhibits Long Bone Growth | Accessory Sex Glands, Tunica Dartos (Scrotum), Semniferous Epithelium, Skeletal Muscle | Anterior Pituitary (Gonadotroph Cells) | Anterior Pituitary (Gonadotroph Cells) | Epididymis | ||||||
Female Target Tissue | Anterior Pituitary (Gonadotroph Cells) | Ovary (Theca Interna and Luteal Cells) | Ovary (Granulosa Cells) | Mammary Cells, Corpus Luteum in Rodents | Uterine Myometrium and Endometrium, Myoepithelial Cells of Mammary Glands | Hypothalamus, Entire Tract, Mammary Gland | Uterine Endometrium, Mammary Gland, Myometrium, Hypothalamus | Brain, Skeletal Muscle, Granulosa Cells | Anterior Pituitary (Gonadotroph Cells) | Anterior Pituitary (Gonadotroph Cells) | Corpus Luteum, Uterine Myometrium, Ovulatory Follicles | Corpus Luteum, Oviduct | Ovary | Ovary | Mammary Gland | |
Male Primary Action | Release of FSH and LH from the Anterior Pituitary Gland | Stimulates Testosterone Production | Sertoli Cell Function | Induce Maternal Behaviour | PGF2α Synthesis, Pre-Ejaculatory Movement of Spermatozoa | Sexual Behaviour | Anabolic Growth, Promotes Spermatogenesis, Promotes Secretion of Accessory Sex Glands | Inhibits FSH Secretion | Stimulates FSH Secretion | Affects Metabolic Activity of Spermatozoa, Epididymal Contractions | Increased Growth of Foetal Testes | |||||
Female Primary Action | Release of FSH and LH from Anterior Pituitary Gland | Stimulates Ovulation, Formation of Corpora Lutea and Progesterone Secretion | Follicular Development, Oestradiol Synthesis | Lactation, Maternal Behaviour, Corpora Lutea Function (some species) | Uterine Motility, Uterine PGF2α Synthesis, Milk Ejection | Sexual Behaviour, GnRH, Elevated Secretory Activity of Tract, Enhanced Uterine Motility | Endometrial Secretion, Inhibits GnRH Release,Inhibits Reproductive Behaviour, Maintenance of Pregnancy | Substrate For E2 Synthesis, Abnormal Masculinization | Inhibits FSH Secretion | Stimulates FSH Secretion | Luteolysis, Uterine Tone and Contraction, Ovulation | Ovulation, Corpus Luteum Secretion of Progesterone | Facilitates Ovarian Production of Progesterone | Formation of Accessory Corpora Lutea | Mammary Stimulation |