Hypersensitivity Flashcards

HYPERSENSITIVITY WIKIBLOOD FLASHCARDS

Hypersensitivity

Question	Answer	Article
What is hypersensitivity?	A hyperactive immune response to an antigen Leading to cell and tissue damage It involves normal immune mechanisms directed towards harmless environmental antigens (ie. allergy) or directed at self antigens (ie. autoimmunity)	Link to Answer Article
Which two scientists proposed the mechanism for distinguishing between the different types of hypersensitivity reactions?	Gell and Coombs	Link to Answer Article
Complete the following sentences	Types I, II and III hypersensitivity are antibody mediated reactions. Type IV hypersensitivity is a cell mediated reaction.	Link to Answer Article

Type I Hypersensitivity

Question	Answer	Article
What is type I hypersensitivity also known as?	Anaphylactic-mediated IgE-mediated	Link to Answer Article
What is the name of antigens which cause type I hypersensitivity?	Allergens	Link to Answer Article
Name some common allergens which cause a type I hypersensitivity reaction	Plant pollens Foods Drugs Proteins Insect products	Link to Answer Article
Mast cells are caused to degranulate releasing cytokines. What affects do these cytokines have on the infected area?	Vasodilation Oedema Mucous production Chemoattractants cause the influx of neutrophils, basophils, monocytes and plasma Vasoactive and inflammatory peptides cause the contraction of smooth muscle fibres	Link to Answer Article
Name some examples of type I hypsensitivity reactions	Sweet-itch Atopy Flea allergic dermatitis	Link to Answer Article

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