Pleural Neoplasia

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()Map CARDIORESPIRATORY SYSTEM (Map)
PLEURAL CAVITY AND MEMBRANES



Primary tumours

  • Rare
  • May arise from chest wall and mediastinum

Mesothelioma

  • Has been found in cat, dog, cow, goat and horse
  • Arise from pericardial, pleural and peritoneal surfaces
  • May be related to inhalation of asbestos
  • Grossly:
    • Multiple discrete nodules
  • Microscopically:
    • Can appear as a carcinoma or fibrosarcoma depending on which tissue, covering or supporting, is predominant in the neoplasm
  • Rarely metastasise but are considered malignant

Secondary tumours

  • Also rare
  • May arise from transpleural dissemination of pulmonary tumours (carcinomas and sarcomas)
  • Carcinomas from abdominal cavity may penetrate through diphragmatic lymphatics