Flaviviridae
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Introduction
This group of viruses has three distinct genera, two of which are of veterinary concern. Flaviviruses, which are endemic vector-borne neurotropic viruses, include louping ill and West Nile Virus. Pestiviruses include Swine Fever and Bovine Virus Diarrhoea and present more hemorrhagic disease. Hepatitis C in man is also grouped in this classification.
Morphology
- Medium sized enveloped viruses
Types and Subtypes
Flaviviruses
Louping Ill
West Nile Virus
Yellow Fever (man)
Pestiviruses
Classical Swine Fever
Border Disease Virus
Bovine Virus Diarrhoea Virus
Pestiviruses
Bovine Viral Diarrhoea & Mucosal Disease Virus may also contribute to Enzootic pneumonia of calves, may cause growth retardation lattice
- Border Disease
- In sheep
- Virus crosses placenta
- Tropism for foetal lymphoid, hair follicle and CNS tissue
- Lambs born weak, small
- Hairy shaker syndrome
- Hair rather than wool coats and cerebellar hypoplasia