Skin Congenital and Hereditary - Pathology
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Acanthosis Nigricans
Alopecia and Hypotrichosis
Collagen Dysplasia
Epidermolysis Bullosa
Epitheliogenesis Imperfecta
Hypertrichosis
- Increased hair growth
- Both congenital or hereditary
- In sheep may be caused by Border Disease virus
- Microscopically:
- Enlarged primary follicles and wool fibres
- Also accociated with maternal hyperthermia
Ichthyosis
- Inherited cutaneous disease
- Occurs in dogs and cattle
- Grossly:
- Thickened skin due to hyperkeratosis
- May crack resembling fish scales
- Increased adherence of keratocytes preventing normal desquamation
- In cattle occurs in two forms:
- Ichthiosis fetalis - fatal, stillborn calves or die within days of birth
- Ichthiosis congenita - folded and thickened skin, fissures and partial alopecia
Porcine Juvenile Pustular Psoriasiform Dermatitis
- Also called Pityriasis Rosea
- Occurs in pigs
- Symmetric lesions on the abdomen, loin and medial thigh
- Start as small papules covered by brown crusts
- -> lesions join and spread -> umbilicated plaques containing white centres with erythematous and scaly borders
- Similar to dermatophytosis
- Histologically:
- Epidermal hyperplasia, parakeratosis, epidermal pustules and superficial perivascular dermatitis
- For more detail see Porcine Juvenile Pustular Psoriasiform Dermatitis
- Occurs in Bullterriers and calves
- Resolves with zinc supplementation in calves but not dogs
- In dogs:
- Fatal acrodermatitis
- Lesions start between digits and on foot pads -> severe interdigital pyoderma -> paronychia and hyperkeratosis of pads
- May also occur on pinnae, elbows, muzzle, hocks or become generalised with crusting, ulceration and secondary pyoderma
- Histologically:
- Hyperkeratosis and bacterial pustular dermatitis