Clostridium piliforme

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Clostridium piliforme
Phylum Firmicutes
Class Clostridia
Order Clostridiales
Family Clostridiaceae
Genus Clostridium
Species piliforme

Also known as: Bacillus piliformis


Clostridium piliforme is a spore-forming filamentous Gram negative intracellular pathogen. The colonies only grow in tissue culture or embryonated eggs. The disease it causes is called Tyzzer's disease characterised by severe hepatic necrosis. It occurs sporadically in foals, calves, dogs and cats. It has an ncubation period up to 1 week.

Diagnosis can be achieved by Warthin-Starry silver impregnation technique demonstrating organisms in hepatocytes.

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Bacillus piliformis/Clostridium piliforme publications