Ameloblastoma, Peripheral

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Neoplastic

Ameloblastoma (Courtesy of Alun Williams (RVC))
  • aka: basal cell carcinoma, acanthomatous ameloblastoma, acanthomatous epulis
  • 18% of cases.
  • Islands and sheets of mature odontogenic epithelium within a collagenous fibrous connective tissue stroma of low/moderate cellularity.
  • Each of the islands bounded by a row of tall columnnar cells.
  • These palisading cells exhibit polarisation away from the basement membrane and had cytoplasmic vacuolation.
  • Central cells had a basaloid appearance.
  • Often infiiltrating into the underlying bone.
  • Synonymous with basal cell carcinoma.

With thanks to Andrew Jefferies (Cambridge) and Alun Williams (RVC) for providing access to their lecture materials