Blastocyst Embryonic Development - Anatomy & Physiology

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  • In the Ootid, male and female pronuclei along with the first and second polar bodies are present.
  • Fusion of male and female pronuclei to form a single diploid nucleus (Syngamy)
  • Zygote (diploid) undergoes mitotic divisions (cleavage).
  • Cleavage gives rise to daughter cells called Blastomeres.


  • Cleavage divisions continue and the 4-celled Embryo gives rise to an 8-celled Embryo.
  • After the 8-celled stage, a ball of cells is formed. This stage is referred to as a Morula.


  • Cells of the Morula continue to devide and a Blastocyst develops, consisting of:
    • Inner Cell Mass (ICM)
    • Blastocoele cavity
    • Single layer of Trophoblast cells
  • Blastocyst 'hatches' from the Zona Pellucida.
  • Blastocyst free-floating within the Uterus.