Ameloblastoma, Peripheral

Ameloblastoma (Courtesy of Alun Williams (RVC))

• aka: basal cell carcinoma, acanthomatous ameloblastoma, acanthomatous epulis
• 18% of cases.
• Islands and sheets of mature odontogenic epithelium within a collagenous fibrous connective tissue stroma of low/moderate cellularity.
• Each of the islands bounded by a row of tall columnnar cells.
• These palisading cells exhibit polarisation away from the basement membrane and had cytoplasmic vacuolation.
• Central cells had a basaloid appearance.
• Often infiiltrating into the underlying bone.
• Synonymous with basal cell carcinoma.

With thanks to Andrew Jefferies (Cambridge) and Alun Williams (RVC) for providing access to their lecture materials