Equine Serum Hepatitis
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- reported in horses given serum of equine origin
- tetanus
- pregnant mare serum
- uknown aetiology
- suggested it may be of infectious cause, perhaps a virus
- disease manifests itself between one to two months post injection
Clinical
- jaundice
- neurological signs
- death follows quickly
Gross
- jaundice
- ascites
- haemorrhages on and in many organs
- liver is greeenish with reddish and pale blotches
- fibrin strands on the liver surface
Microscopically
- liver cells very fatty (large single vacuoles), some degenerated and a few leukocytes
- moderate portal fibrosis
- heavily bile stained