Cholangitis

• Inflammation of the bile ducts

• • common in cats
  • calves eg Salmonella sp.

Causes

• ascending infections from the intestine
  • requires stasis of bile flow to develop
• associated with organisms excreted via the bile
  • salmonellosis infection in calves

Cats

• • • cholangitis
    • periportal hepatocellular necrosis
    • neutrophils in the portal areas
    • acute or chronic.
    • Usually male, pure bred
    • Cats more ill than lymphocytic portal hepatitis.
    • Higher ALT and serum bilirubin levels.

Chronic lymphocytic cholangitis

• mature cats

Microscopically

• lymphocytic infiltration of the portal areas
• mild fibrosis
• biliary hyperplasia