Angiotensin Converting Enzyme

ACE

  • Membrane bound metalloproteinase
  • Converts Angiotensin 1 to Angiotensin 2
  • Very important in the Renin Angiotensin Aldosterone System (RAAS)
  • Predominantly expressed on epithelial cell membranes in the pulmonary ciculation
  • The site of action of the group of drugs - ACE inhibitors