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Also known as: Infectious Canine Laryngotracheitis
Antigenicity
- Some antigenicity shared between CAV 1 and 2, which lends to vaccination
Pathogenesis
- Causes necrosis of the respiratory tract with NO concurrent hepatitis
- Animals present with:
- Pyrexia
- Mild depression
- Nasal/ocular discharges
- Corneal opacity (not always)
- Dry, harsh, persistent cough
Epidemiology
- Transfer is same as for CAV 1
Diagnosis
- Virus isolation from respiratory secretions
Control
- Isolate coughing dogs and disinfect premises
- Vaccination: CAV 1 vaccine will cross protect
- Adenoviridae
- Usually mild bronchointerstitial pneumonia, necrosis of bronchiolar and alveolar epithelium, oedema, type II pneumocyte hyperplasia
- May cause necrotising bronchiolitis in immune-deficient dogs (distemper)
- Can be associated with kennel cough described above