Rhabdoviridae
Rabies is a neurological killer that has evolved a fool-proof technique of transmission, and it cleverly evades the species barrier to present a potent threat to mammalian life. While the simplicity of the virus ensures its transmission, it also contributes to its weakness: its monoclonal antigenicity means that a single vaccination covers all strains of the disease. Though rabies is considered endemic in parts of the developed and undeveloped world, vaccination schemes have rendered the disease controllable to a satisfactory degree. Nonetheless, infection is still largely fatal and the disease should not be taken lightly.
Morphology
- Large, enveloped, negative-sense RNA virus
- Bullet-shaped with short glycoprotein spikes
Types and Subtypes
Two Genera:
- Lyssaviruses: 7 genotypes
- Genotype 1 is classical rabies
- Genotypes 2-7 more limited in distribution
- Genotype 4 infects insectivorous bats
- Vesiculoviruses are all exotic to the UK:
- Vesicular Stomatitis Virus
- Ephemeral Fever
- Fish Rhabdoviruses, such as viral hemorrhagic syndrome and infectious haematopoetic necrosis virus
Rhabdoviridae Learning Resources | |
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Pages in category "Rhabdoviridae"
The following 4 pages are in this category, out of 4 total.