- Occurs in horses, dogs, cats and humans
- Caused by dematiaceous fungi:
- Exophilia jeanselmeri, Phialophora, Cladosporium carrionii, Fonsecaea pedrosoi
- Enters tissue through wounds or sites of tissue trauma
- Limited to subcutaneous and cutaneous tissues
- Causes hyperplasia and formation of verrucoid, warty nodules
- Warts are irregular, vegetative and pedunculated
- Spread is via the lymphatic system
- Dissemination to other tissues and organs can occur
- Chronic condition which will progress if not treated
- Treatment includes Ketoconazole, 5-fluorocytosine and amphotericin B