Eosinophilic Granuloma

This is a complex of diseases affecting skin and oral cavity mainly of cat, which include:

1. Oral eosinophilic granuloma
2. Linear granuloma of skin
3. Eosinophilic plaque of skin

Clinical

• Any age, but usually young adults.
• Mainly affects lips, may also occasionally affect frenulum of tongue.
• Sometimes called "rodent ulcer "
• Not neoplastic - it is an inflammatory disease but is progressive and destructive.

• May see small plaque or becomes very infiltrative.
• In worst cases may erode away whole nose.

Pathogenesis

• Histologically lots of eosinophils, polymorphs.
• Exaggerated eosinophilic response.