Eosinophilic Granuloma

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This is a complex of diseases affecting skin and oral cavity mainly of cat, which include:

  1. Oral eosinophilic granuloma
  2. Linear granuloma of skin
  3. Eosinophilic plaque of skin

Clinical

  • Any age, but usually young adults.
  • Mainly affects lips, may also occasionally affect frenulum of tongue.
  • Sometimes called "rodent ulcer "
  • Not neoplastic - it is an inflammatory disease but is progressive and destructive.
  • May see small plaque or becomes very infiltrative.
  • In worst cases may erode away whole nose.

Pathogenesis

  • Histologically lots of eosinophils, polymorphs.
  • Exaggerated eosinophilic response.