Gastritis, Chronic Atrophic

• Aetiology uncertain.
• Grossly: (may be difficult to appreciate)
  • Reduced mucosal thickness.
  • Loss of rugae.
• Histologically
  • Mucosal thinning.
  • Loss of gastric glands.
  • Diffuse inflammatory infiltrate of lymphocytes and plasma cells.
  • Fewer eosinophils in lamina propria.