Non-Infectious Arthritis

• No causative agent has been found
• Seem to be immune-mediated diseases

Erosive

Non-erosive

Systemic lupus erythematosus (SLE)

• Occurs in dogs
• Clinical signs:
  • Anaemia
  • Thrombocytopaenia
  • Polymyositis
  • Glomerulonephritis

In chronic diseases

• E.g. pyometra, otitis externa, endocarditis, enteritis
• Can lead to immune complex deposition in joints

Gout

• Occurs in humans, reptiles and birds (have no uricase enzyme)
• The urate triggers inflammation