[[Anal Sac Adenocarcinoma|Anal sac adenocarcinoma]] is a highly malignant neoplasia that readily metastasizes to the medial iliac lymph nodes. Around 50% may lead to paraneoplastic hypercalcaemia due to parathyroid hormone-related peptide (PTH-rP). The tumours can be between 1 and 10cm in size and 50% of them will metastasize | [[Anal Sac Adenocarcinoma|Anal sac adenocarcinoma]] is a highly malignant neoplasia that readily metastasizes to the medial iliac lymph nodes. Around 50% may lead to paraneoplastic hypercalcaemia due to parathyroid hormone-related peptide (PTH-rP). The tumours can be between 1 and 10cm in size and 50% of them will metastasize |