Changes

==Pituitary Hypofunction==

==Pituitary Hypofunction==

===Congenital Panhypopituitarism===

===[[Congenital Panhypopituitarism]]===

Also known as ''Pituitary Dwarfism'', Congenital Panhypopituitarism is defined by failure of differentiation of oesophageal ectoderm from which the pituitary is derived.  The pituitary is replaced by a cystic dilatation of ''Rathke's Cleft'' which replaces normal tissue with multilocular cysts- lined with non-secretory cuboidal epithelium.   

Also known as ''Pituitary Dwarfism'', Congenital Panhypopituitarism is defined by failure of differentiation of oesophageal ectoderm from which the pituitary is derived.  The pituitary is replaced by a cystic dilatation of ''Rathke's Cleft'' which replaces normal tissue with multilocular cysts- lined with non-secretory cuboidal epithelium.   

*Progestagens may induce GH production from the mammary gland.

*Progestagens may induce GH production from the mammary gland.

*May need to replace thyroid hormones and/or glucocorticoids.

*May need to replace thyroid hormones and/or glucocorticoids.

===Pituitary cysts===

===Pituitary cysts===

*The '''cranio-pharyngeal ducts''' which are the route by which the developing anterior pituitary ascends from the pharynx.  The craniopharyngeal ducts are the neck of Rathke's pouch which, during development, narrows, closes and separates the vesicle of Rathke's pouch from the oral cavity.  These cysts have columnar ciliated epithelial cells lining the cyst and contain mucin.  <br>The craniopharyngeal ducts may also become neoplastic; '''Craniopharyngioma'''.  These tumours contain single or multiple cysts.

*The '''cranio-pharyngeal ducts''' which are the route by which the developing anterior pituitary ascends from the pharynx.  The craniopharyngeal ducts are the neck of Rathke's pouch which, during development, narrows, closes and separates the vesicle of Rathke's pouch from the oral cavity.  These cysts have columnar ciliated epithelial cells lining the cyst and contain mucin.  <br>The craniopharyngeal ducts may also become neoplastic; '''Craniopharyngioma'''.  These tumours contain single or multiple cysts.

*'''Rathke's Pouch''' which may fail to differentiate and becomes cystic.

*'''Rathke's Pouch''' which may fail to differentiate and becomes cystic.

===Pituitary Neoplasia===

===Pituitary Neoplasia===

*Surrounding brain tissue.

*Surrounding brain tissue.

*Ependyma.

*Ependyma.

====Pituitary neoplasia in the horse====

====Pituitary neoplasia in the horse====

*Hirsutism.

*Hirsutism.

*Hyperhidrosis.

*Hyperhidrosis.

==Pituitary Hyperfunction==

==Pituitary Hyperfunction==

*In the adult results in '''Acromegaly'''.   

*In the adult results in '''Acromegaly'''.   

===Acromegaly===

===[[Acromegaly]]===