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Canine Dermatomyositis (view source)
Revision as of 16:53, 22 February 2011
, 16:53, 22 February 2011no edit summary
*Affects puppies of collies and shetland sheepdogs from 8 weeks of age
*Affects puppies of collies and shetland sheepdogs from 8 weeks of age
*Lesions - vesiculating dermatitis
*Lesions - vesiculating dermatitis
**Face, lips, external ears, later distal extremities
**Face, lips, external ears, later distal extremities
*Microscopically: interface dermatitis and basal cell degeneration of epidermis and follicular wall, atrophy of follicles, epidermal vesicles and pustules, dermal scarring
*Microscopically: interface dermatitis and basal cell degeneration of epidermis and follicular wall, atrophy of follicles, epidermal vesicles and pustules, dermal scarring
*Hereditary in Collies and Shetland sheepdgs
*Lesions resemble [[Muscles Inflammatory - Pathology#Canine polymyositis|canine polymyositis]]
*Also degeneration of blood vessels -> muscle [[Muscles Degenerative - Pathology#Ischaemia|microinfarcts]]
*Usually generalised but temporalis and other masticatory muscles may be involved the most
*Microscopically: inclusion bodies in endothelial cells
*Best place for biopsy is anterior and most superficial temporalis muscle
*Also involves skin, may involve the oesophagus
[[Category:Integumentary System - Autoimmune Reactions]]
[[Category:Integumentary System - Autoimmune Reactions]]