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Bones Inflammatory - Pathology (view source)
Revision as of 17:35, 27 February 2011
, 17:35, 27 February 2011no edit summary
*Most infections are exacerbated by host response
*Most infections are exacerbated by host response
*Pathogenesis:
*Pathogenesis:
**Prostaglandin and cytokines stimulate [[Bones - normal#Normal structure|osteoclastic]] bone resorption
**Prostaglandin and cytokines stimulate [[Bones - Anatomy & Physiology|osteoclastic]] bone resorption
**Blood vessel occlusion and tissue necrosis -> lack of removal of agent and cartilage -> cartilage thickening + persistance of infection
**Blood vessel occlusion and tissue necrosis -> lack of removal of agent and cartilage -> cartilage thickening + persistance of infection
*Affected area may be surrounded by fibrous inflammatory tissue
*Affected area may be surrounded by fibrous inflammatory tissue