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Created page with "*Also called heterotopic mineralisation (calcification) *Deposition of calcium phosphate, silicate and other in unusual locations *Contrast with [[Bones Hyperplastic and Neoplast..."
*Also called heterotopic mineralisation (calcification)
*Deposition of calcium phosphate, silicate and other in unusual locations
*Contrast with [[Bones Hyperplastic and Neoplastic - Pathology#Ectopic ossification|ectopic ossification]]
*Can be
**Idiopathic
***''E.g.'' primary tumoral calcinosis (see below)
**Metastatic
***''E.g.'' Associated with hypercalcaemia of uraemia and [[Hypervitaminosis D|hypervitaminosis D]]
**Dystrophic
***''E.g.'' due to repetitive trauma
*'''Calcinosis cutis'''
**Associated with [[Hyperadrenocorticism|hyperadrenocorticism]], exposure to calcium chloride and wet concrete
**Also present in some normal poodles
*'''Calcinosis circumscripta''' ('''tumoral calcinosis''')
**Usually single lesion in skin of extremities of dogs
**May occur in vertebral region and cause ataxia
**In horses mainly 2-4 years old at lateral stifle, not attached to skin
**May be the result of repetitive trauma (''e.g.'' in supraspinatus tendon in hunting or working dogs)
**Grossly:
***Nodular masses about 1cm across or few cm more
***May ulcerate
***White, soft creamy or dry gritty on cutting
**Microscopically:
***Amorphous and granular mineralised areas
***Surrounded by connective tissue
***Granulomatous reaction is common
***Chronic lesions may contain metaplastic cartilage or bone
[[Category:Bones - Pathology]]
*Deposition of calcium phosphate, silicate and other in unusual locations
*Contrast with [[Bones Hyperplastic and Neoplastic - Pathology#Ectopic ossification|ectopic ossification]]
*Can be
**Idiopathic
***''E.g.'' primary tumoral calcinosis (see below)
**Metastatic
***''E.g.'' Associated with hypercalcaemia of uraemia and [[Hypervitaminosis D|hypervitaminosis D]]
**Dystrophic
***''E.g.'' due to repetitive trauma
*'''Calcinosis cutis'''
**Associated with [[Hyperadrenocorticism|hyperadrenocorticism]], exposure to calcium chloride and wet concrete
**Also present in some normal poodles
*'''Calcinosis circumscripta''' ('''tumoral calcinosis''')
**Usually single lesion in skin of extremities of dogs
**May occur in vertebral region and cause ataxia
**In horses mainly 2-4 years old at lateral stifle, not attached to skin
**May be the result of repetitive trauma (''e.g.'' in supraspinatus tendon in hunting or working dogs)
**Grossly:
***Nodular masses about 1cm across or few cm more
***May ulcerate
***White, soft creamy or dry gritty on cutting
**Microscopically:
***Amorphous and granular mineralised areas
***Surrounded by connective tissue
***Granulomatous reaction is common
***Chronic lesions may contain metaplastic cartilage or bone
[[Category:Bones - Pathology]]