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Bone Response to Damage (view source)
Revision as of 15:07, 28 September 2007
, 15:07, 28 September 2007no edit summary
*Two main types of bone development:
*Two main types of bone development:
**'''Endochondral ossification''' (cartilage model)
**'''Endochondral ossification''' (cartilage model)
***Long bones mainly
***Long bones mainly - physis and metaphysis
***Mesenchymal cells differentiate into chondroblasts
****Produce scaffold of mineralised cartilage on which osteoblasts deposit bone
***Vascularised
***Vascularised
***Developed centres of ossification
***Developed centres of ossification
****Secondary (epiphyseal)
****Secondary (epiphyseal)
**'''Intramembranous ossification'''
**'''Intramembranous ossification'''
***Flat bones mainly (e.g. skull)
***Flat bones mainly (e.g. skull), shaft of long bones
***Mesenchymal cells differentiate into osteoblasts
***Mesenchymal cells differentiate into osteoblasts
***No cartilage precursor template
***No cartilage precursor template