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Created page with "*'''Azoturia''' (Monday morning disease) **Acute **Due to exercise following a prolonged period of rest **Clincal signs: ***Unable to move ***Sweating ***Tremors ***Swollen and h..."
*'''Azoturia''' (Monday morning disease)
**Acute
**Due to exercise following a prolonged period of rest
**Clincal signs:
***Unable to move
***Sweating
***Tremors
***Swollen and hard lumbar, gluteal and femoral muscles
**Myoglobin leaks from muscle cells -> leaks into urine -> urine is dark red/brown (myoglobinuria) -> damages renal tubules
**Grossly:
***Salmon pink muscles -> dark, moist, swollen +/- pale streaks
**Histologically:
***Segmental myofibre [[Muscles Degenerative - Pathology#Necrosis|necrosis]]
****Multifocal and monophasic, but may be multiphasic if repeated bouts
***Both, type IIA and IIB fibres affected; type IIB preferentially affected in acute disease
***Minor inflammatory reaction and calcification
*'''Tying-up'''
**Similar to azoturia but much milder
**Grossly - normal muscle
**Histologically - same as azoturia
[[Category:Muscles - Degenerative Pathology]]
**Acute
**Due to exercise following a prolonged period of rest
**Clincal signs:
***Unable to move
***Sweating
***Tremors
***Swollen and hard lumbar, gluteal and femoral muscles
**Myoglobin leaks from muscle cells -> leaks into urine -> urine is dark red/brown (myoglobinuria) -> damages renal tubules
**Grossly:
***Salmon pink muscles -> dark, moist, swollen +/- pale streaks
**Histologically:
***Segmental myofibre [[Muscles Degenerative - Pathology#Necrosis|necrosis]]
****Multifocal and monophasic, but may be multiphasic if repeated bouts
***Both, type IIA and IIB fibres affected; type IIB preferentially affected in acute disease
***Minor inflammatory reaction and calcification
*'''Tying-up'''
**Similar to azoturia but much milder
**Grossly - normal muscle
**Histologically - same as azoturia
[[Category:Muscles - Degenerative Pathology]]