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CNS Response to Injury - Pathology (view source)

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~~|linkpage = Nervous System - Pathology~~

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==Introduction==

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*#* Choroid plexus epithelial cells

* The response to injury varies with the cell type injured.

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==Response ~~of Neurons~~ to Injury==

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==[[Neuron Response to Injury]]==

* Neurons are particularly vulnerable to injury, due to their:

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** It may sometimes be a normal feature.

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==Glial Cell Response to Injury==

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[[Category:CNS Response to Injury]]

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==[[Glial Cell Response to Injury]]==

* The order of susceptibility of CNS cells to injury runs, from most to least susceptible:

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*#* These are small nodules that occur notably in viral diseases.

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==General Responses to Injury==

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[[Category:CNS Response to Injury]]

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==[[General CNS Responses to Injury]]==

===Ischaemic Damage===

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*** Cyanide poisoning, which inhibits tissue respiration

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==Excitotoxicity==

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[[Category:CNS Response to Injury]]

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==[[Excitotoxicity]]==

* The term "excitotoxicity" is used to describe the process by which neurons are damaged by glutamate and other similar substances.

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*#*** These enzymes go on to damage cell structures such as components of the cytoskeleton, membrane, and DNA.

* Excitotoxicity is, therefore, a cause of acute neuron death.

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[[Category:CNS Response to Injury]]

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