Changes

Also known as: '''''Rodent ulcer — Eosinophilic ulcer — Eosinophilic plaques — Eosinophilic granuloma'''''

Also known as: '''''Rodent ulcer — Eosinophilic ulcer — Eosinophilic plaques — Eosinophilic granuloma'''''

Feline eosinophilic granuloma complex includes three types of lesions:  

Feline eosinophilic granuloma complex includes three types of lesions:  

#Eosinophilic ulcer which present as a well circumscribed, erythematous ulcer on the lip or oral mucosa of middle-aged cats  

#Eosinophilic '''ulcer''' which present as a well circumscribed, erythematous ulcer on the lip or oral mucosa of middle-aged cats  

#[[Eosinophilic Plaques|Eosinophilic plaques]] which present as raised erythematous lesions on the skin of the medial thighs and abdomen  

#[[Eosinophilic Plaques|Eosinophilic '''plaques''']] which present as raised erythematous lesions on the skin of the medial thighs and abdomen  

#Eosinophilic granuloma which present on the posterior aspect of the rear legs of young cats and also found on the [[Tongue - Anatomy & Physiology|tongue]], [[Hard Palate|hard palate]] and oral mucosa.

#Eosinophilic '''granuloma''' which present on the posterior aspect of the rear legs of young cats and also found on the [[Tongue - Anatomy & Physiology|tongue]], [[Hard Palate|hard palate]] and oral mucosa.

Eosinophilic granulomas of the '''oral cavity''' appear as '''yellow/pink raised linear lesions'''. They can also occur on the soft palate, or the base of the tongue. Cats with eosinophilic lesions of the mouth often have concurrent skin lesions.  

Eosinophilic granulomas of the '''oral cavity''' appear as '''yellow/pink raised linear lesions'''. They can also occur on the soft palate, or the base of the tongue. Cats with eosinophilic lesions of the mouth often have concurrent skin lesions.  

The cause of feline eosinophilic granuloma is unknown but it has been associated with food and insect bite allergies, atopy, immunosuppression, bacteral and viral infections.  

The cause of feline eosinophilic granuloma is unknown but it has been associated with food and insect bite allergies, atopy, immunosuppression, bacterial and viral infections.  

 

== Signalment ==

== Signalment ==

More commonly found in young cats (2-6 years) and also more common in females than males.  

More commonly found in young cats (2-6 years) and also more common in females than males.  

Depending on site of lesion can include dysphagia, halitosis and anorexia.  

 

Depending on site of lesion can include dysphagia, halitosis and anorexia. <br>

 

== Diagnosis ==

== Diagnosis ==

An ulcerated mass may be found at the base of the tongue or on the hard palate, the glossopalatine arches or anywhere else in the mouth as described above. On laboratory tests, a peripheral blood [[Eosinophilia|eosinophilia]] may be present.  

An ulcerated mass may be found at the base of the tongue or on the hard palate, the glossopalatine arches or anywhere else in the mouth as described above. On laboratory tests, a peripheral blood [[Eosinophilia|eosinophilia]] may be present.  

== Pathology ==

== Pathology ==

A deep biopsy specimen of the mass is required for a definitive diagnosis. Histology reveals an eosinophilic tissue infiltrate and polymorphs are present. There is also an exaggerated eosinophilic response.  

A deep biopsy specimen of the mass is required for a definitive diagnosis. Histology reveals an eosinophilic tissue infiltrate and polymorphs are present. There is also an exaggerated eosinophilic response.  

== Treatment ==

== Treatment ==

Surgical excision is required for large lesions that interfere with breathing or swallowing.  

Surgical excision is required for large lesions that interfere with breathing or swallowing.  

== Prognosis ==

== Prognosis ==

Good but the lesion can recur.  

Good but the lesion can recur.  

== Literature Search ==

== Literature Search ==

<br> Use these links to find recent scientific publications via CAB Abstracts (log in required unless accessing from a subscribing organisation). <br><br><br> [http://www.cabdirect.org/search.html?q=%28title%3A%28%22Eosinophilic+Granuloma%22%29+OR+title%3A%28%22Rodent+ulcer%22%29+OR+title%3A%28%22Eosinophilic+ulcer%22%29+OR+title%3A%28%22Eosinophilic+plaques%22%29%29+AND+od%3A%28cats%29 Feline Eosinophilic Granuloma publications]  

<br> Use these links to find recent scientific publications via CAB Abstracts (log in required unless accessing from a subscribing organisation). <br><br><br> [http://www.cabdirect.org/search.html?q=%28title%3A%28%22Eosinophilic+Granuloma%22%29+OR+title%3A%28%22Rodent+ulcer%22%29+OR+title%3A%28%22Eosinophilic+ulcer%22%29+OR+title%3A%28%22Eosinophilic+plaques%22%29%29+AND+od%3A%28cats%29 Feline Eosinophilic Granuloma publications]  

== References ==

== References ==

 

[[Category:Integumentary_System_-_Pathology]] [[Category:Oral_Cavity_and_Gingiva_-_Pathology]] [[Category:Oral_Diseases_-_Cat]] [[Category:Dermatological_Diseases_-_Cat]] [[Category:To_Do_-_Review]] [[Category:Allergic_Skin_Diseases]]

[[Category:Integumentary_System_-_Pathology]] [[Category:Oral_Cavity_and_Gingiva_-_Pathology]] [[Category:Oral_Diseases_-_Cat]] [[Category:Dermatological_Diseases_-_Cat]] [[Category:Expert_Review - Small Animal]] [[Category:Allergic_Skin_Diseases]]