Later in the disease course the [[Lymph Nodes - Anatomy & Physiology|lymph nodes]] and [[Spleen - Anatomy & Physiology|spleen]] shrink due to '''lymphoid exhaustion'''. | Later in the disease course the [[Lymph Nodes - Anatomy & Physiology|lymph nodes]] and [[Spleen - Anatomy & Physiology|spleen]] shrink due to '''lymphoid exhaustion'''. |