Post-synaptic receptors determine the reaction of the neurotransmitter meaning that the same neurotransmitter may cause an excitatory effect on some membranes whilst exerting an inhibitory effect on others e.g ACH can be either excitatory to skeletal muscle cells or inhibitory to both smooth muscle and cardiac muscle. | Post-synaptic receptors determine the reaction of the neurotransmitter meaning that the same neurotransmitter may cause an excitatory effect on some membranes whilst exerting an inhibitory effect on others e.g ACH can be either excitatory to skeletal muscle cells or inhibitory to both smooth muscle and cardiac muscle. |