Changes

**Viraemia

**Viraemia

**Spreads via monocytes to a variety of epithelium depending upon the strain of virus  

**Spreads via monocytes to a variety of epithelium depending upon the strain of virus  

**[[Nasal cavity - inflammatory#Infectious causes of rhinitis|Respiratory]] and alimentary tracts, skin and later (1-5 wk. post infection) to the brain

**[[Viral infections#Canine distemper|Respiratory]] and alimentary tracts, skin and later (1-5 wk. post infection) to the brain

*'''Clinical signs''':

*'''Clinical signs''':

**Mucopurulent oculonasal discharge  

**Mucopurulent oculonasal discharge