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**Lesions in the tongue, cheek, lips and sometimes in the lower gut and lungs from aspiration
 
**Lesions in the tongue, cheek, lips and sometimes in the lower gut and lungs from aspiration
 
**Often spreads from the site of infection to lymphatics, and may cause pyogranulomatous lymphadenitis
 
**Often spreads from the site of infection to lymphatics, and may cause pyogranulomatous lymphadenitis
**[[Muscles - inflammatory#Wooden tongue|myositis]] and formation of fibrous tissue in the lesions lead to hardening of the tissue, hence the condition is known as 'wooden tongue' in cattle
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**[[Muscles - inflammatory#Wooden tongue|Myositis]] and formation of fibrous tissue in the lesions lead to hardening of the tissue, hence the condition is known as 'wooden tongue' in cattle
 
**In sheep abscesses with thick walls are produced
 
**In sheep abscesses with thick walls are produced
 
**Feeding is impaired, causing loss of condition
 
**Feeding is impaired, causing loss of condition
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**Potentiated sulphonamides or a penicillin/streptomycin combination
 
**Potentiated sulphonamides or a penicillin/streptomycin combination
 
**Rough feed should be avoided
 
**Rough feed should be avoided
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===''Actinobacillus equuli''===
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*Commensal of the equine intestinal mucosa
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*Infection at birth causes severe enteritis and septicaemia within 24 hours, known as sleepy foal disease
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*In foals that survive neonatal infection the condition progresses to cause joint infections and purulent nephritis
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*''A. equuli'' in [[Joints - inflammatory#In Horses|arthritis of horses]]
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*RTX group cytotoxin present
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===''Actinobacillus suis''===
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*Fatal septicaemia in pigs 1-8 weeks old
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*Causes abscesses in joints and lungs of older pigs
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*Carried in the nasopharynx of pigs and nose of horses
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*Carriage may confer immunity to the more severe pleuropneumonia
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**ApxIII is a cytotoxin
 
**ApxIII is a cytotoxin
 
**Different ''Actinobacillus pleuropneumonia'' serotypes secrete a particular combination of toxins; American serotypes secrete ApxI and II; European serotypes secrete ApxII and III
 
**Different ''Actinobacillus pleuropneumonia'' serotypes secrete a particular combination of toxins; American serotypes secrete ApxI and II; European serotypes secrete ApxII and III
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===''Actinobacillus equuli''===
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 +
*Commensal of the equine intestinal mucosa
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*Infection at birth causes severe enteritis and septicaemia within 24 hours, known as sleepy foal disease
 +
*In foals that survive neonatal infection the condition progresses to cause joint infections and purulent nephritis
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*''A. equuli'' in [[Joints - inflammatory#In Horses|arthritis of horses]]
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*Abortion in mares
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*Septicaemia in piglets
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*Arthritis and enteritis in pigs
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*Enteritis in calves
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*RTX group cytotoxin present
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===''Actinobacillus suis''===
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 +
*Fatal septicaemia in piglets 1-8 weeks old
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*Causes abscesses in joints and lungs of older pigs
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*Carried in the nasopharynx of pigs and nose of horses
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*Carriage may confer immunity to the more severe pleuropneumonia
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*Septicaemia and pneumonia in foals
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*Pneumonia in pigs and horses
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===''Actinobacillus seminis''===
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*Epididymitis in rams
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*Polyarthritis in lambs
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===''Actinobacillus actinomycetemcomitans''===
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*Epididymitis in rams
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