Changes

Clinical signs due to a hypothalamic dysfunction.   

Clinical signs due to a hypothalamic dysfunction.   

Decresaed synthesis and release of GnRH means that the pituitary is not stimulated to release FSH or LH at normal levels.  Clincally seen as:

Decreased synthesis and release of GnRH means that the pituitary is not stimulated to release FSH or LH at normal levels.  Clinically seen as:

*Small, atrophic genitals.

*Small, atrophic genitals.

*Feminisation in the male due to lower testosterone release.

*Feminisation in the male due to lower testosterone release.

Hypothalamus damage also allows incresaed appetite and the animal will be:

Hypothalamus damage also allows increased appetite and the animal may be obese, with excess deposition of subcutaneous fat.

*Excess deposition of sub-cut fat.

Compression of local structures also leads to:

Compression of local structures also leads to:

*Mental retartdation.

*Mental retardation.

*Diabetes insipidus.

*Diabetes insipidus.

*Visual impairment.

*Visual impairment.