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Major Histocompatability Complexes (view source)
Revision as of 10:59, 16 May 2012
, 10:59, 16 May 2012→TCR-MHC Interaction
Only peptide associated with MHC will interact with and activate [[T cells]]. T cells therefore cannot be directly activated by a peptide on a foreign organism.
Only peptide associated with MHC will interact with and activate [[T cells]]. T cells therefore cannot be directly activated by a peptide on a foreign organism.
T cells will react against foreign MHC molecules and this is the basis of graft rejection
T cells will react against foreign MHC molecules (e.g. from a different person) and this is the basis of graft rejection, for example in Heart transplants.
==MHC Genetics (Polymorphism)==
==MHC Genetics (Polymorphism)==