495
edits
Changes
→TH2 Cells
==T<sub>H</sub>2 Cells==
==T<sub>H</sub>2 Cells==
[[Image:TH2-Bcell.jpg|thumb|right|200px|TH2 cells incite increased antibody production - B. Catchpole, RVC 2008]]
[[Image:TH2-Bcell.jpg|thumb|right|200px|T<sub>H</sub>2 cells incite increased antibody production - B. Catchpole, RVC 2008]]
T<sub>H</sub>2 cells help [[B cells]] produce antibody where the organism is present in tissue fluid. The T<sub>H</sub>2 population influences B cell activation, proliferation and immunoglobulin production. T<sub>H</sub>2 T cells also secrete a range of cytokines:
T<sub>H</sub>2 cells help [[B cells]] produce antibody where the organism is present in tissue fluid. The T<sub>H</sub>2 population influences B cell activation, proliferation and immunoglobulin production. T<sub>H</sub>2 T cells also secrete a range of cytokines:
#'''IL-4''' which stimulates B cell growth and induces the heavy chain switch from [[Immunoglobulin M|IgM]] to [[Immunoglobulin G|IgG]] , [[Immunoglobulin A|IgA]] and [[Immunoglobulin E|IgE]], as well as proliferation of basophils and mast cells. IL-4 can inhibit some T cell responses.
#'''IL-4''' which stimulates B cell growth and induces the heavy chain switch from [[Immunoglobulin M|IgM]] to [[Immunoglobulin G|IgG]] , [[Immunoglobulin A|IgA]] and [[Immunoglobulin E|IgE]], as well as proliferation of basophils and mast cells. IL-4 can inhibit some T cell responses.