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Mycobacterium avium complex (view source)

Revision as of 08:21, 28 June 2006

658 bytes added , 08:21, 28 June 2006

→‎Johne's disease

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==MAC group generalities==

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*Share many of the same properties, so often referred to as the M.avium-intracellulare complex (MAIC)

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*Dogs and cats very resistant to infection with MAIC

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**Siamese cats are predisposed to getting disseminated disease.

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*Ubiquitous, saprophytic causing disease in immunocompromised hosts.

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*Genetic susceptibility for disseminated disease in:

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**Humans, rabbits, Basset hounds and mice

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***Susceptibility identified by the Bcg locus in mice.

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*In most mammals infection results in granulomatous inflammation with little necrosis, calcification or fibrosis. Lymph nodes are usually involved. Dissemination by hematogenous route later.

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==Johne's disease==

*Caused by Mycobacterium avium subsp. paratuberculosis

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