290
edits
Changes
Jump to navigation
Jump to search
→Johne's disease
==MAC group generalities==
*Share many of the same properties, so often referred to as the M.avium-intracellulare complex (MAIC)
*Dogs and cats very resistant to infection with MAIC
**Siamese cats are predisposed to getting disseminated disease.
*Ubiquitous, saprophytic causing disease in immunocompromised hosts.
*Genetic susceptibility for disseminated disease in:
**Humans, rabbits, Basset hounds and mice
***Susceptibility identified by the Bcg locus in mice.
*In most mammals infection results in granulomatous inflammation with little necrosis, calcification or fibrosis. Lymph nodes are usually involved. Dissemination by hematogenous route later.
==Johne's disease==
==Johne's disease==
*Caused by Mycobacterium avium subsp. paratuberculosis
*Caused by Mycobacterium avium subsp. paratuberculosis