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Also known as: '''''Lymphocytic-plasmacytic cholangitis —Cholangiohepatitis — Non-suppurative cholangitis'''''
Also known as: '''''Lymphocytic-plasmacytic cholangitis —Cholangiohepatitis — Non-suppurative cholangitis'''''
==Description==
==Introduction==
'''Lymphocytic cholangitis''' is a slowly progressive chronic disease characterised by infiltration of the portal areas of the liver with inflammatory cells, mostly [[Lymphocytes - Introduction|lymphocytes]] and [[B cell differentiation#Plasma cells|plasma cells]]. Bile duct hypertrophy and [[Liver Fibrosis|fibrosis]] are present. However, lymphocytic cholangitis does not progress to biliary [[Cirrhosis|cirrhosis]]. An immune-mediated aetiology has been postulated but this has not been substantiated to date. It is rarely associated with [[Pancreatitis|pancreatitis]], compared to [[Cholangitis, Neutrophilic]]
'''Lymphocytic cholangitis''' is a slowly progressive chronic disease characterised by infiltration of the portal areas of the liver with inflammatory cells, mostly [[Lymphocytes - Introduction|lymphocytes]] and [[B cell differentiation#Plasma cells|plasma cells]]. Bile duct hypertrophy and [[Liver Fibrosis|fibrosis]] are present. However, lymphocytic cholangitis does not progress to biliary [[Cirrhosis|cirrhosis]]. An immune-mediated aetiology has been postulated but this has not been substantiated to date. It is rarely associated with [[Pancreatitis|pancreatitis]], compared to [[Cholangitis, Neutrophilic]]
Poor due to the waxing and waning feature of this disease. In cats, this disease does not usually progress to end-stage cirrhosis and therefore it does not usually result in death, which is in contrast to dogs.
Poor due to the waxing and waning feature of this disease. In cats, this disease does not usually progress to end-stage cirrhosis and therefore it does not usually result in death, which is in contrast to dogs.
{{Learning
|literature search = [http://www.cabdirect.org/search.html?rowId=1&options1=AND&q1=Cholangitis&occuring1=title&rowId=2&options2=AND&q2=Lymphocytic&occuring2=title&rowId=3&options3=AND&q3=&occuring3=freetext&publishedstart=yyyy&publishedend=yyyy&calendarInput=yyyy-mm-dd&la=any&it=any&show=all&x=48&y=8 Lymphocytic Choloangitis publications]
}}
[http://www.cabdirect.org/search.html?rowId=1&options1=AND&q1=Cholangitis&occuring1=title&rowId=2&options2=AND&q2=Lymphocytic&occuring2=title&rowId=3&options3=AND&q3=&occuring3=freetext&publishedstart=yyyy&publishedend=yyyy&calendarInput=yyyy-mm-dd&la=any&it=any&show=all&x=48&y=8 Lymphocytic Choloangitis publications]
==References==
==References==
Marks, S.L. (2003). '''Update on the Diagnosis and Management of Feline Cholangiohepatitis''' ''Waltham Feline Medicine Symposium''.
Marks, S.L. (2003). '''Update on the Diagnosis and Management of Feline Cholangiohepatitis''' ''Waltham Feline Medicine Symposium''.
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[[Category:Gall_Bladder_and_Tract_-_Pathology]]]]
[[Category:Gall_Bladder_and_Tract_-_Pathology]]]]
[[Category:Gall Bladder and Tract Diseases - Cat]][[Category:Gall Bladder and Tract Diseases - Dog]]
[[Category:Gall Bladder and Tract Diseases - Cat]][[Category:Gall Bladder and Tract Diseases - Dog]]
[[Category:Expert_Review]]
[[Category:Expert_Review]]