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| + | ==Overview== |
| + | |
| + | * Steroid hormone |
| + | * Secreted from the zona glomerulosa of the adrenal cortex of the adrenal gland |
| + | * Mineralocorticoid |
| + | * Most important regulator of plasma pottassium |
| + | * Stimulated directly by increased plasma pottassium |
| + | * Also stimulated as part of the [[Renin-Angiotensin-Aldosterone System (RAAS) - Anatomy & Physiology | Renin-Angiotensin-Aldosterone System (RAAS)]] |
| + | |
| + | |
| + | ==Action== |
| + | |
| + | * Works by altering gene transcription |
| + | ** Affects ATP levels |
| + | |
| + | ===Sodium=== |
| + | |
| + | * Affects sodium entry and transport |
| + | * Increases sodium re-uptake to a small degree in distal convoluted tubule |
| + | |
| + | |
| + | ===Pottassium and Hydrogen=== |
| + | |
| + | * Causes pottassium and hydrogen secretion |
| + | ** Pottassium via apical leak channels |
| + | ** Hydrogen by proton secretory proteins |