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Sexual Differentiation - Anatomy & Physiology
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Revision as of 13:29, 3 July 2008
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13:29, 3 July 2008
→Sexual Differentiation of the Brain
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== Sexual Differentiation of the Brain ==
== Sexual Differentiation of the Brain ==
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'''MALE'''
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* '''Testosterone''' secreted into the blood reaches the brain.
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* Converted to Dehydrotestosterone and '''Oestradiol''' by Aromatase enzymes in the Hypothalamus.
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* Oestradiol masculinises the brain
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'''FEMALE'''
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* '''Alpha Fetoprotein''' binds Oestradiol, preventing it from crossing the blood-brain barrier.
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* Oestradiol cannot access the Hypothalamus
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* Protects female brain from masculising effects of Oestradiol.
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Lwilkie
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