Changes

* Formation of B cells and T cells ([[Leukopoiesis#Lymphopoiesis|Lymphopoiesis]])

* Formation of B cells and T cells ([[Leukopoiesis#Lymphopoiesis|Lymphopoiesis]])

== Hematopoyesis and Distribution of Cells in the Body (NW) ==

== Hematopoyesis and Distribution of Cells in the Body ==

Erythrocytes, platelets and granulocytes (neutrophils, eosinophils and basophils) are derived from pluripotential stem cells. These give rise to multipotential colony-forming unit progenitors for granulocytes, erythrocytes, monocytes/macrophages and megakaryocytes. Under the influence of interleukins and colony-stimulating factors, committed stem cells develop into differentiated blood cells (erythrocytes, neutrophils, eosinophils, basophils, monocytes and platelets). Neutrophils and monocytes develop from the same colony-forming unit. Although the bone marrow produces some lymphocytes most are derived from the peripheral lymphoid tissue.

Erythrocytes, platelets and granulocytes (neutrophils, eosinophils and basophils) are derived from pluripotential stem cells. These give rise to multipotential colony-forming unit progenitors for granulocytes, erythrocytes, monocytes/macrophages and megakaryocytes. Under the influence of interleukins and colony-stimulating factors, committed stem cells develop into differentiated blood cells (erythrocytes, neutrophils, eosinophils, basophils, monocytes and platelets). Neutrophils and monocytes develop from the same colony-forming unit. Although the bone marrow produces some lymphocytes most are derived from the peripheral lymphoid tissue.

Haematopoiesis may occur in other organs particularly the spleen, less frequently the liver and even peripheral lymph nodes, if there is a marked increase in demand for cells. With increased tissue demands, mature reserves are depleted and immature cells are released into the circulation.

Haematopoiesis may occur in other organs particularly the spleen, less frequently the liver and even peripheral lymph nodes, if there is a marked increase in demand for cells. With increased tissue demands, mature reserves are depleted and immature cells are released into the circulation.

[[File:NWL 2016 Labfacts inners A4 PRESS optimize(40).jpg|thumb|Bone Marrow Citology and Histology]]

[[File:NWL 2016 Labfacts inners A4 PRESS optimize(40).jpg|thumb|Bone Marrow Citology and Histology]]

[[File:NWL 2016 Labfacts inners A4 PRESS optimize(90).jpg|thumb|Bone Marrow Histology]]

[[File:NWL 2016 Labfacts inners A4 PRESS optimize(90).jpg|thumb|Bone Marrow Histology|link=Special:FilePath/NWL_2016_Labfacts_inners_A4_PRESS_optimize(90).jpg]]

==Foetal Haematopoiesis==

==Foetal Haematopoiesis==