This enzyme is present in high concentrations in a wide range of organs and tissues including red blood cells. It is found in the cell cytoplasm and is released into the blood during changes in cell membrane permeability or necrosis. Five isoenzymes are recognised including heart, liver and muscle. | This enzyme is present in high concentrations in a wide range of organs and tissues including red blood cells. It is found in the cell cytoplasm and is released into the blood during changes in cell membrane permeability or necrosis. Five isoenzymes are recognised including heart, liver and muscle. |