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*Emesis is the process of vomiting
 
*Emesis is the process of vomiting
 +
 +
*Persistant vomiting can be exhausting and can lead to metabolic alkalosis, dehydration and electrolyte inbalances which may require fluid therapy
 +
 +
*Extreme cases of persistant vomiting can lead to shock
    
*Retching involves the abdominal and chest walls contracting
 
*Retching involves the abdominal and chest walls contracting
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*Inputs also from inner ear and higher centres
 
*Inputs also from inner ear and higher centres
 +
 +
*Emetic agents can be used in cases of gastric obstruction and to remove non-corrosive poisons from the stomach (for corrosive poisons charcoal can be used which will help absorb the substance and decrease its absorbtion into the GIT)
 +
 +
*Drugs cause emesis by irritating the gastric mucosa
    
*Emetic agents
 
*Emetic agents
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**Catecholamines
 
**Catecholamines
 
**5-hydroxytryptamine
 
**5-hydroxytryptamine
 +
**Substance P
 +
**Enkephalins
 +
**NK1 receptor agonists
 +
 +
*Anti-emetic agents can be used to treat motion sickness and to treat or prevent vomiting
    
*Anti-emetic agents
 
*Anti-emetic agents
(INCLUDE HERE)
+
**Dopamine (D2) receptor antagonists
 +
**5-hydroxytryptamine antagonists
 +
**NK1 receptor antagonists
 +
**Muscarinic receptor antagonists
 +
**Histamine (H1) receptor antagonists
 +
**Gastroprotective agents
    
==Species Differences==
 
==Species Differences==
3,326

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