*Persistant vomiting can be exhausting and can lead to metabolic alkalosis, dehydration and electrolyte inbalances which may require fluid therapy
+
+
*Extreme cases of persistant vomiting can lead to shock
*Retching involves the abdominal and chest walls contracting
*Retching involves the abdominal and chest walls contracting
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*Inputs also from inner ear and higher centres
*Inputs also from inner ear and higher centres
+
+
*Emetic agents can be used in cases of gastric obstruction and to remove non-corrosive poisons from the stomach (for corrosive poisons charcoal can be used which will help absorb the substance and decrease its absorbtion into the GIT)
+
+
*Drugs cause emesis by irritating the gastric mucosa
*Emetic agents
*Emetic agents
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**Catecholamines
**Catecholamines
**5-hydroxytryptamine
**5-hydroxytryptamine
+
**Substance P
+
**Enkephalins
+
**NK1 receptor agonists
+
+
*Anti-emetic agents can be used to treat motion sickness and to treat or prevent vomiting