* Total quantity of sodium is conserved not the actual plasma concentration
* Total quantity of sodium is conserved not the actual plasma concentration
−
** This is because water follows sodium so the volume is altered according to the amount of sodium
+
** When sodium is reabsorbed water follows it so the volume of the plasma is altered rather than the concentration of sodium changing
−
** [[Renin-Angiotensin-Aldosterone System (RAAS) - Anatomy & Physiology| Angiotensin 2]] and aldosterone also affect ECF so only quantity affected not concentration
+
** [[Renin-Angiotensin-Aldosterone System (RAAS) - Anatomy & Physiology| Angiotensin 2]] and [[Aldosterone]] affect scodium but they also affect ECF volume so only quantity affected not concentration
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** ADH and thirst response also work together to dilute the ECF so although there is more NaCl the actual concentration is constant.
+
** ADH and thirst response also work together to dilute the ECF if concentrations of sodium is high so although there is more NaCl the actual concentration is not really changed.
* If there was no secretion of aldosterone a 20kg dog would excrete 15g per 24 hours
* If there was no secretion of aldosterone a 20kg dog would excrete 15g per 24 hours
* At maximal secretion no significant amount of sodium would be excreted
* At maximal secretion no significant amount of sodium would be excreted