Changes

<p>The differentiated cells that remain in the cortex become memory cells and these proliferate and form germinal centres in the [[Lymph Nodes - Anatomy & Physiology|lymph node]].</p>

<p>The differentiated cells that remain in the cortex become memory cells and these proliferate and form germinal centres in the [[Lymph Nodes - Anatomy & Physiology|lymph node]].</p>

<p>Memory cells are long lived and responsible for long term immunity providing the immune system with a memory of previously encountered antigens. When they experience an antigen again they proliferate and differentiate into plasma cells. This response produces up to ten times more plasma cells than the original exposure to the antigen and is why the second immune response to an antigen is both more rapid and much stronger than the first response.</p>

<p>Memory cells are long lived and responsible for long term immunity providing the immune system with a memory of previously encountered antigens. When they experience an antigen again they proliferate and differentiate into plasma cells. This response produces up to ten times more plasma cells than the original exposure to the antigen and is why the second immune response to an antigen is both more rapid and much stronger than the first response.</p>